Researchers look at cell relationships and function to determine new breast cancer therapies
Mar 15, 2012
A new study conducted by researchers at the University of Kentucky found new treatment strategies to combat basal-like breast cancer, which is also known as triple-negative breast cancer. The researchers discovered this by looking at the way certain cells connect with one another and their relationships. By creating a new E-cadherin molecule, which binds cells together like Snail and the G9a enzyme, researchers can help treat the cancer.
"This finding has significant clinical ramification, because chemical compounds or agents that can disrupt the interaction of Snail with G9a will have a great therapeutic potential of treating triple-negative breast cancer," said Peter Zhou, principal investigator for the study. "Investigators at the Markey Cancer Center are currently exploring this idea and are keen to develop drugs that can treat triple-negative breast cancer."
According to the American Cancer Society, breast cancer is the second leading cause of cancer-related death among women, following only lung cancer. However, the death rate has been decreasing since 1990 due to advancements in research and breakthrough breast cancer news. There are currently 2.5 million survivors in the United States.