Study shows men do not respond well to breast cancer drug tamoxifen
Nov 21, 2011
A recent study found that the breast cancer treatment tamoxifen does not work well on men with the disease. The study, which is published in the Annals of Oncology, found that one in five men who are treated with this drug discontinue it soon after.
The researchers from the Anderson Cancer Center in Houston discovered that the reasoning behind the men discontinuing the drug included negative toxic effects. More than half - 53 percent - of the 126 men in the study experienced weight gain, sexual dysfunction, hot flashes, neurocognitive deficits, thromboembolic events and ocular events. In addition, a quarter of the men developed metastatic disease or recurrence during the study.
According to the American Cancer Society, even though it is much more common for women to be diagnosed with breast cancer, men can still get the disease as well. One in eight women will be diagnosed with the disease, compared to the one in 1,000 men in the U.S. that will suffer from breast cancer during their lifetime.